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Thoughts from methods development, collaboration and data science practice

How can we combine multiple estimators of the same estimand to minimize variance?

October 21, 2026

A short derivation of the best linear combination of correlated estimators, including the case of a vector parameter.

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September 25, 2026

Use coefficient variances and covariances to derive pointwise confidence limits for a fitted line or polynomial curve, with reproducible R examples.

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February 16, 2025

A GLM perspective on Cox partial likelihood, bypassing risk-set construction and event-conditioning arguments.

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February 10, 2025

An intuitive way to ask investigators about correlation when planning studies with repeated measurements.

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January 16, 2025

Calculate agreement statistics and create faceted Bland–Altman plots for multiple biomarkers using tidyverse tools.

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December 20, 2024

Use list-columns and purrr::map() to generate datasets, fit models, and summarize simulation results.

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